The Silenced .22 is a firearm in Condemned 2: Bloodshot. It deals the lowest amount of damage of all other guns but is fairly accurate at long distances. It features a high rate of fire and a high magazine capacity (15 rounds).

The .22 Pistol is a rare firearm, found only in the Bowling Alley level. It appears to be a modeled after the Ruger Mk III .22-Caliber Semi-Automatic pistol with an attached sound suppressor.

When playing FPS Mode, Ethan will begin the Trenton District level with the Silenced .22.